What do sufferers of schizophrenia experience, and why? Might the immune system be to blame? And could an avatar be the answer to treatment? This week we delve deep into the brain circuitry behind one of the most common psychiatric conditions to uncover the causes, hear what drugs like ketamine can reveal about hallucinations and how a cartoon representation of the voices plaguing patients can block the symptoms. Plus, chemically induced pluripotent stem cells, a gene that leads carriers into snacking temptation and why babies can tolerate extended periods upside down inside their mothers...?